TBHP-promoted sequential radical silylation and aromatisation of aryl isonitriles with silanes.

نویسندگان

  • Lei Wang
  • Hui Zhu
  • Songjin Guo
  • Jiang Cheng
  • Jin-Tao Yu
چکیده

The tert-butyl hydroperoxide (TBHP) promoted sequential silylation and aromatisation of isonitriles was developed, where the silyl group was regioselectively installed at the 6-position of phenanthridines. This procedure tolerates a series of functional groups, such as fluoro, chloro, acetyl, methoxy carbonyl, cyano and trifluoromethyl. The addition of a silyl radical to the isonitrile followed by an intramolecular aromatic cyclization was involved in this transformation.

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عنوان ژورنال:
  • Chemical communications

دوره 50 74  شماره 

صفحات  -

تاریخ انتشار 2014